When planning a health promotion program for adolescents, which primary prevention strategy is most effective in addressing substance abuse?

The correct answer to the question "When planning a health promotion program for adolescents, which primary prevention strategy is most effective in addressing substance abuse?" is Option B: Providing education on refusal skills and healthy coping mechanisms..

The other options — A) Implementing random drug testing in schools., C) Focusing on rehabilitation programs for substance users., D) Promoting strict zero-tolerance policies with severe penalties. — are incorrect for this NCLEX-RN Exam Prep question. As explained above: Equipping adolescents with refusal skills, decision-making abilities, and healthy coping mechanisms is a primary prevention strategy that addresses underlying factors contributing to substance abuse.