Thin-layer chromatography (TLC) separates compounds based on:

A Size only

B Differential affinity for the stationary phase (silica) vs. the mobile phase (solvent)

C Charge only

D Molecular weight only

✓ Correct Answer: Option B

TLC: polar compounds have higher affinity for silica (low Rf). Nonpolar compounds travel further with nonpolar solvent (higher Rf).

💡 Why is B) the correct answer?

The correct answer to the question "Thin-layer chromatography (TLC) separates compounds based on:" is Option B: Differential affinity for the stationary phase (silica) vs. the mobile phase (solvent).

The other options — A) Size only, C) Charge only, D) Molecular weight only — are incorrect for this PCAT Exam Prep question. As explained above: TLC: polar compounds have higher affinity for silica (low Rf). Nonpolar compounds travel further with nonpolar solvent (higher Rf).

📚 About This PCAT Exam Prep Practice Question

This 2-level PCAT Exam Prep question from the Chemical Processes topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free PCAT Exam Prep practice test or use flashcards for spaced repetition review.

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Thin-layer chromatography (TLC) separates compounds based on:

✓ Correct Answer: Option B

📚 About This PCAT Exam Prep Practice Question

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