💊 PCAT Exam Prep

The isoelectric point (pI) of an amino acid is:

A Always pH 7
B The pH at which the amino acid has no net charge (zwitterion, equal + and − charges)
C The pH of denaturation
D The pH of maximum solubility

✓ Correct Answer: Option B

pI = average of the two relevant pKa values. At pI, amino acid exists as a zwitterion with zero net charge.

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