💊 PCAT Exam Prep

Competitive antagonists:

A Decrease maximum response

B Bind reversibly to the receptor, shifting the dose-response curve rightward (higher EC50, same Emax)

C Bind irreversibly

D Increase receptor number

✓ Correct Answer: Option B

Competitive antagonist: can be overcome by increasing agonist concentration. Right shift of curve, Emax unchanged.