🎓 IB Exam Prep

An enzyme functions optimally at a pH of 7.4 and a temperature of 37°C. What would most likely happen to its activity if the pH was lowered to 2.0?

A Its activity would increase due to higher proton concentration.
B It would denature, leading to a significant loss of activity.
C Its activity would remain unchanged as pH only affects active site binding.
D It would speed up its denaturation process at 37°C.

✓ Correct Answer: Option B

Enzymes are sensitive to pH changes. A significant deviation from the optimal pH alters the charge distribution on amino acids, disrupting the enzyme's 3D structure and active site, leading to denaturation and loss of activity.

Related IB Exam Prep Questions