Which of the following neurotransmitters is most strongly implicated in the pathophysiology of schizophrenia, particularly in relation to its positive symptoms?

✓ Correct Answer: Option D

The dopamine hypothesis of schizophrenia posits that positive symptoms (hallucinations, delusions) are caused by excessive dopaminergic activity in the mesolimbic pathway. Antipsychotics primarily block dopamine D2 receptors.