Which of the following cell types primarily presents antigens via MHC class I molecules?

A B lymphocytes

B Macrophages

C Dendritic cells

D All nucleated cells

✓ Correct Answer: Option D

MHC class I molecules are expressed on virtually all nucleated cells and present endogenous antigens (from inside the cell) to CD8+ cytotoxic T lymphocytes.

💡 Why is D) the correct answer?

The correct answer to the question "Which of the following cell types primarily presents antigens via MHC class I molecules?" is Option D: All nucleated cells.

The other options — A) B lymphocytes, B) Macrophages, C) Dendritic cells — are incorrect for this USMLE Exam Prep question. As explained above: MHC class I molecules are expressed on virtually all nucleated cells and present endogenous antigens (from inside the cell) to CD8+ cytotoxic T lymphocytes.

📚 About This USMLE Exam Prep Practice Question

This 2-level USMLE Exam Prep question from the Step 1 – Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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Which of the following cell types primarily presents antigens via MHC class I molecules?

✓ Correct Answer: Option D

📚 About This USMLE Exam Prep Practice Question

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