🏥 USMLE Exam Prep

Which immunoglobulin class is most abundant in serum?

A IgM
B IgG — it is the most abundant and provides secondary immune response
C IgA
D IgE

✓ Correct Answer: Option B

IgG: most abundant serum immunoglobulin (~75%), crosses placenta, provides secondary (memory) immune response. IgM = primary response. IgA = mucosal. IgE = allergic/parasitic.

💡 Why is B) the correct answer?

The correct answer to the question "Which immunoglobulin class is most abundant in serum?" is Option B: IgG — it is the most abundant and provides secondary immune response.

The other options — A) IgM, C) IgA, D) IgE — are incorrect for this USMLE Exam Prep question. As explained above: IgG: most abundant serum immunoglobulin (~75%), crosses placenta, provides secondary (memory) immune response. IgM = primary response. IgA = mucosal. IgE = allergic/parasitic.

📚 About This USMLE Exam Prep Practice Question

This 2-level USMLE Exam Prep question from the Step 1 - Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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