🏥 USMLE Exam Prep

Which immunoglobulin class is most abundant in serum?

A IgM
B IgG — it is the most abundant and provides secondary immune response
C IgA
D IgE

✓ Correct Answer: Option B

IgG: most abundant serum immunoglobulin (~75%), crosses placenta, provides secondary (memory) immune response. IgM = primary response. IgA = mucosal. IgE = allergic/parasitic.

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