Which enzyme converts angiotensin I to angiotensin II?

A Renin

B Angiotensin-converting enzyme (ACE) located primarily in pulmonary vasculature

C Aldosterone synthase

D Angiotensinogen

✓ Correct Answer: Option B

RAAS: renin (from JGA) cleaves angiotensinogen → angiotensin I. ACE (in lung endothelium) converts AT-I → AT-II. AT-II causes vasoconstriction and aldosterone release. ACE inhibitors block this step.

💡 Why is B) the correct answer?

The correct answer to the question "Which enzyme converts angiotensin I to angiotensin II?" is Option B: Angiotensin-converting enzyme (ACE) located primarily in pulmonary vasculature.

The other options — A) Renin, C) Aldosterone synthase, D) Angiotensinogen — are incorrect for this USMLE Exam Prep question. As explained above: RAAS: renin (from JGA) cleaves angiotensinogen → angiotensin I. ACE (in lung endothelium) converts AT-I → AT-II. AT-II causes vasoconstriction and aldosterone release. ACE inhibitors block this step.

📚 About This USMLE Exam Prep Practice Question

This 3-level USMLE Exam Prep question from the Step 1 - Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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Which enzyme converts angiotensin I to angiotensin II?

✓ Correct Answer: Option B

📚 About This USMLE Exam Prep Practice Question

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