🏥 USMLE Exam Prep

Which enzyme converts angiotensin I to angiotensin II?

A Renin
B Angiotensin-converting enzyme (ACE) located primarily in pulmonary vasculature
C Aldosterone synthase
D Angiotensinogen

✓ Correct Answer: Option B

RAAS: renin (from JGA) cleaves angiotensinogen → angiotensin I. ACE (in lung endothelium) converts AT-I → AT-II. AT-II causes vasoconstriction and aldosterone release. ACE inhibitors block this step.

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