What is the greatest common factor (GCF) of 48 and 64? A 8 B 12 C 16 D 4 ✓ Correct Answer: Option C 48 = 2⁴ × 3; 64 = 2⁶. GCF = 2⁴ = 16. Practice ACT Exam Prep Quizzes → Browse All Questions Study Flashcards