Warfarin inhibits coagulation by:

A Directly inhibiting thrombin

B Blocking vitamin K epoxide reductase, preventing synthesis of factors II, VII, IX, and X

C Activating antithrombin III

D Inhibiting platelet aggregation

✓ Correct Answer: Option B

Warfarin: vitamin K antagonist → inhibits gamma-carboxylation of factors II, VII, IX, X and proteins C/S. Monitored by INR/PT. Onset delayed (factor half-lives). Bridge with heparin initially.

💡 Why is B) the correct answer?

The correct answer to the question "Warfarin inhibits coagulation by:" is Option B: Blocking vitamin K epoxide reductase, preventing synthesis of factors II, VII, IX, and X.

The other options — A) Directly inhibiting thrombin, C) Activating antithrombin III, D) Inhibiting platelet aggregation — are incorrect for this USMLE Exam Prep question. As explained above: Warfarin: vitamin K antagonist → inhibits gamma-carboxylation of factors II, VII, IX, X and proteins C/S. Monitored by INR/PT. Onset delayed (factor half-lives). Bridge with heparin initially.

📚 About This USMLE Exam Prep Practice Question

This 3-level USMLE Exam Prep question from the Step 1 - Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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Warfarin inhibits coagulation by:

✓ Correct Answer: Option B

📚 About This USMLE Exam Prep Practice Question

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