🏥 USMLE Exam Prep

The majority of DNA viruses replicate their genome in the nucleus of the host cell. Which of the following DNA viruses is a notable exception to this rule, replicating primarily in the cytoplasm?

A Herpes simplex virus
B Adenovirus
C Poxvirus
D Papillomavirus

✓ Correct Answer: Option C

Poxviruses are unique among DNA viruses because they replicate their entire life cycle, including DNA replication, within the cytoplasm of the host cell. Most other DNA viruses, like herpes simplex, adenovirus, and papillomavirus, replicate in the nucleus.

💡 Why is C) the correct answer?

The correct answer to the question "The majority of DNA viruses replicate their genome in the nucleus of the host cell. Which of the following DNA viruses is a notable exception to this rule, replicating primarily in the cytoplasm?" is Option C: Poxvirus.

The other options — A) Herpes simplex virus, B) Adenovirus, D) Papillomavirus — are incorrect for this USMLE Exam Prep question. As explained above: Poxviruses are unique among DNA viruses because they replicate their entire life cycle, including DNA replication, within the cytoplasm of the host cell. Most other DNA viruses, like herpes simplex, …

📚 About This USMLE Exam Prep Practice Question

This 1-level USMLE Exam Prep question from the Step 1 – Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

Related USMLE Exam Prep Questions