🏥 USMLE Exam Prep

Rheumatoid arthritis characteristically affects joints in a pattern that is:

A Unilateral large joints
B Symmetric involvement of small joints, particularly the MCPs and PIPs of the hands
C Asymmetric spine involvement
D Only the knees

✓ Correct Answer: Option B

RA: chronic symmetric inflammatory polyarthritis. Targets MCPs, PIPs, wrists. Spares DIPs (OA affects DIPs). Swan neck, boutonniere deformities. RF and anti-CCP antibodies. DMARDs: methotrexate first-line.

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