🏥 USMLE Exam Prep

In a double-blind randomized controlled trial:

A Only the patient is blinded
B Neither the patients nor the investigators know who receives the treatment or placebo
C Only the researcher is blinded
D No one is involved

✓ Correct Answer: Option B

Double-blind RCT: participants AND researchers unaware of allocation. Minimizes placebo effect and observer bias. Gold standard for clinical trials. Single-blind: only participant unaware.

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