🏥 USMLE Exam Prep

*Corynebacterium diphtheriae* produces a toxin that inhibits protein synthesis in host cells by inactivating elongation factor-2 (EF-2). This mechanism directly impacts which cellular process?

A DNA replication
B RNA transcription
C Ribosomal translation
D Mitochondrial ATP production

✓ Correct Answer: Option C

Elongation factor-2 (EF-2) is crucial for the translocation step during ribosomal protein synthesis (translation). Inactivation of EF-2 by diphtheria toxin halts protein production, leading to cell death.

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