An increase in end-diastolic volume directly leads to an increase in stroke volume by stretching cardiac muscle fibers. This phenomenon is best described by which of the following principles?

The correct answer to the question "An increase in end-diastolic volume directly leads to an increase in stroke volume by stretching cardiac muscle fibers. This phenomenon is best described by which of the following principles?" is Option B: Frank-Starling mechanism.

The other options — A) Poiseuille's Law, C) Laplace's Law, D) Bernoulli's principle — are incorrect for this USMLE Exam Prep question. As explained above: The Frank-Starling mechanism states that the stroke volume of the heart increases in response to an increase in the volume of blood filling the heart (the end-diastolic volume) when all other factors…