An 82-year-old patient with multiple comorbidities (hypertension, osteoarthritis, anxiety) presents with frequent falls in the past 3 months. Her medication list includes lisinopril, ibuprofen, and lorazepam 0.5 mg daily. What is the most appropriate initial intervention to reduce her fall risk related to medication?

The correct answer to the question "An 82-year-old patient with multiple comorbidities (hypertension, osteoarthritis, anxiety) presents with frequent falls in the past 3 months. Her medication list includes lisinopril, ibuprofen, and lorazepam 0.5 mg daily. What is the most appropriate initial intervention to reduce her fall risk related to medication?" is Option D: Discontinue lorazepam.

The other options — A) Discontinue lisinopril, B) Switch lorazepam to an antidepressant, C) Reduce ibuprofen dose — are incorrect for this USMLE Exam Prep question. As explained above: Benzodiazepines like lorazepam significantly increase fall risk in the elderly due to their sedative and psychomotor impairing effects. Discontinuing or deprescribing such medications is a crucial in…