🏥 USMLE Exam Prep

Administration of a loop diuretic will directly inhibit the reabsorption of which of the following in the thick ascending limb of the loop of Henle?

A Na+/H+ antiporter
B Na+/K+/2Cl- cotransporter
C Na+/Cl- cotransporter
D Aldosterone-sensitive Na+ channel

✓ Correct Answer: Option B

Loop diuretics (e.g., furosemide) inhibit the Na+/K+/2Cl- cotransporter in the luminal membrane of the thick ascending limb, leading to increased excretion of Na+, K+, and Cl-, as well as Ca2+ and Mg2+.

💡 Why is B) the correct answer?

The correct answer to the question "Administration of a loop diuretic will directly inhibit the reabsorption of which of the following in the thick ascending limb of the loop of Henle?" is Option B: Na+/K+/2Cl- cotransporter.

The other options — A) Na+/H+ antiporter, C) Na+/Cl- cotransporter, D) Aldosterone-sensitive Na+ channel — are incorrect for this USMLE Exam Prep question. As explained above: Loop diuretics (e.g., furosemide) inhibit the Na+/K+/2Cl- cotransporter in the luminal membrane of the thick ascending limb, leading to increased excretion of Na+, K+, and Cl-, as well as Ca2+ and Mg…

📚 About This USMLE Exam Prep Practice Question

This 3-level USMLE Exam Prep question from the Step 1 – Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

Related USMLE Exam Prep Questions