🏥 USMLE Exam Prep

A patient with hypertension and angina is prescribed metoprolol. What is the primary mechanism of action of this drug?

A Direct arterial vasodilation
B Inhibition of angiotensin-converting enzyme
C Selective antagonism of beta-1 adrenergic receptors
D Blockade of calcium channels in cardiac muscle

✓ Correct Answer: Option C

Metoprolol is a selective beta-1 adrenergic receptor antagonist (beta-blocker). It primarily blocks beta-1 receptors in the heart, decreasing heart rate, contractility, and blood pressure, which is beneficial for hypertension and angina.

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