🏥 USMLE Exam Prep

A patient with essential hypertension is prescribed metoprolol. Which of the following is the primary mechanism by which metoprolol reduces blood pressure?

A Direct vasodilation by blocking alpha-1 receptors
B Increased renal sodium excretion
C Selective antagonism of beta-1 adrenergic receptors in the heart
D Inhibition of angiotensin-converting enzyme (ACE)

✓ Correct Answer: Option C

Metoprolol is a selective beta-1 adrenergic receptor antagonist. By blocking beta-1 receptors in the heart, it decreases heart rate and myocardial contractility, leading to a reduction in cardiac output and blood pressure.

Related USMLE Exam Prep Questions