A patient with chronic alcoholism presents with ataxia, nystagmus, and confusion. This Wernicke-Korsakoff syndrome is primarily due to a deficiency of which vitamin, acting as a coenzyme for pyruvate dehydrogenase?

✓ Correct Answer: Option B

Thiamine (Vitamin B1) is a crucial coenzyme for several enzymes, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, both vital for glucose metabolism in the brain. Deficiency leads to impaired energy production and neurological symptoms.