🏥 USMLE Exam Prep

A patient undergoes a tuberculin skin test (PPD). A positive result, characterized by induration and erythema 48-72 hours after injection, indicates which type of hypersensitivity reaction?

A Type I (Immediate)
B Type II (Cytotoxic)
C Type III (Immune Complex)
D Type IV (Delayed-Type)

✓ Correct Answer: Option D

The PPD test is a classic example of a Type IV, or delayed-type, hypersensitivity reaction. It involves T-cell activation and macrophage recruitment, leading to a visible reaction hours to days after antigen exposure.

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