🏥 USMLE Exam Prep

A patient presents with severe dehydration. Which of the following physiological responses would be expected to occur in the kidney to conserve water?

A Increased release of Atrial Natriuretic Peptide (ANP)
B Decreased collecting duct permeability to water
C Increased reabsorption of sodium in the thick ascending limb
D Increased release of Antidiuretic Hormone (ADH)

✓ Correct Answer: Option D

Severe dehydration increases plasma osmolarity, stimulating the release of ADH. ADH increases water reabsorption in the collecting ducts by increasing their permeability to water via aquaporin channels, thereby conserving body water.

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