🏥 USMLE Exam Prep

A patient presents with hyperkalemia and metabolic acidosis. Laboratory tests reveal low plasma renin activity and low aldosterone levels. Which of the following conditions is most consistent with these findings?

A Primary hyperaldosteronism (Conn's syndrome)
B Addison's disease
C Renal tubular acidosis Type 1
D Hyporeninemic hypoaldosteronism

✓ Correct Answer: Option D

Hyporeninemic hypoaldosteronism is characterized by low renin levels, which subsequently leads to low aldosterone. This impairs renal potassium and hydrogen ion excretion, resulting in hyperkalemia and metabolic acidosis, often seen in elderly diabetics.

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