🏥 USMLE Exam Prep

A patient presents with a resting tremor, bradykinesia, and rigidity. Imaging reveals degeneration of dopaminergic neurons in the substantia nigra. These symptoms are primarily due to a deficiency in which neurotransmitter in the basal ganglia?

A Serotonin
B Acetylcholine
C Dopamine
D GABA

✓ Correct Answer: Option C

Parkinson's disease is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to a deficiency of dopamine in the basal ganglia. This dopamine deficiency results in the characteristic motor symptoms.

💡 Why is C) the correct answer?

The correct answer to the question "A patient presents with a resting tremor, bradykinesia, and rigidity. Imaging reveals degeneration of dopaminergic neurons in the substantia nigra. These symptoms are primarily due to a deficiency in which neurotransmitter in the basal ganglia?" is Option C: Dopamine.

The other options — A) Serotonin, B) Acetylcholine, D) GABA — are incorrect for this USMLE Exam Prep question. As explained above: Parkinson's disease is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to a deficiency of dopamine in the basal ganglia. This dopamine deficie…

📚 About This USMLE Exam Prep Practice Question

This 2-level USMLE Exam Prep question from the Step 1 – Basic Sciences topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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