🏥 USMLE Exam Prep

A patient is treated with ciprofloxacin for a bacterial infection. What is the primary mechanism of action of ciprofloxacin?

A Inhibition of bacterial cell wall synthesis
B Disruption of bacterial ribosomal protein synthesis
C Inhibition of bacterial DNA gyrase and topoisomerase IV
D Interference with folic acid synthesis

✓ Correct Answer: Option C

Ciprofloxacin belongs to the fluoroquinolone class of antibiotics. Its primary mechanism of action involves inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes crucial for DNA replication, transcription, and repair.

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