A patient is prescribed a non-selective beta-blocker for hypertension. Which of the following adverse effects is most likely due to its action on beta-2 adrenergic receptors?

✓ Correct Answer: Option B

Non-selective beta-blockers block beta-2 receptors in the bronchial smooth muscle, leading to bronchoconstriction. This effect is particularly concerning for patients with asthma or COPD.