A patient experiences an acute hemolytic transfusion reaction following administration of incompatible blood. This reaction is primarily mediated by antibodies binding to antigens on red blood cells, leading to complement activation and cellular destruction. This scenario represents which type of hypersensitivity reaction?
✓ Correct Answer: Option B
Type II hypersensitivity involves antibodies (IgG or IgM) binding to cell surface antigens, leading to cell destruction via complement activation, opsonization, or antibody-dependent cellular cytotoxicity (ADCC).