A patient develops hemolytic anemia following a blood transfusion due to ABO incompatibility. This reaction is primarily mediated by which type of hypersensitivity?

✓ Correct Answer: Option B

Type II hypersensitivity involves antibody-mediated cytotoxicity, where antibodies (e.g., anti-A or anti-B) bind to antigens on cell surfaces (e.g., red blood cells), leading to cell lysis via complement activation or phagocytosis.