🏥 USMLE Exam Prep

A pathologist observes cells under a microscope showing cytoplasmic eosinophilia, nuclear pyknosis, karyorrhexis, and karyolysis. These findings are most consistent with which cellular process?

A Apoptosis
B Hyperplasia
C Necrosis
D Metaplasia

✓ Correct Answer: Option C

Cytoplasmic eosinophilia, nuclear pyknosis (shrinkage), karyorrhexis (fragmentation), and karyolysis (dissolution) are classic morphological changes observed in cells undergoing necrosis, indicating irreversible cell injury and death.

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