🏥 USMLE Exam Prep

A new diagnostic test for a rare disease has a sensitivity of 95% and a specificity of 90%. If the disease prevalence in the population is 1%, what does a high positive predictive value (PPV) for this test indicate?

A The probability that a person without the disease tests negative.
B The proportion of true positives among all individuals with the disease.
C The probability that a person with a positive test result actually has the disease.
D The likelihood of developing the disease after exposure to a risk factor.

✓ Correct Answer: Option C

Positive predictive value (PPV) is the probability that an individual who tests positive truly has the disease. It is heavily influenced by the prevalence of the disease in the population, decreasing with lower prevalence.

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