A histological examination of lung tissue from a long-term smoker reveals enlarged airspaces distal to the terminal bronchioles and destruction of alveolar walls. This description is most consistent with which pathological condition?
✓ Correct Answer: Option C
Emphysema is characterized by irreversible enlargement of airspaces distal to the terminal bronchioles, accompanied by destruction of their walls without obvious fibrosis. Smoking is a primary cause.