🏥 USMLE Exam Prep

A gram-negative bacterial infection causes septic shock in a patient. Which component of the bacterial cell wall is primarily responsible for triggering this severe inflammatory response?

A Peptidoglycan
B Teichoic acid
C Lipopolysaccharide (LPS)
D Capsule

✓ Correct Answer: Option C

Lipopolysaccharide (LPS), specifically its Lipid A component, is found in the outer membrane of gram-negative bacteria. It acts as an endotoxin, triggering a potent innate immune response and systemic inflammation, leading to septic shock.

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