A genetic disorder characterized by a CGG trinucleotide repeat expansion in the 5' untranslated region of the FMR1 gene, leading to anticipation and intellectual disability, is most consistent with which diagnosis?

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B) Fragile X Syndrome. Fragile X Syndrome is caused by a CGG trinucleotide repeat expansion in the FMR1 gene's 5' UTR, leading to gene silencing and intellectual disability. It is a classic example of anticipation.

A genetic disorder characterized by a CGG trinucleotide repeat expansion in the 5' untranslated region of the FMR1 gene, leading to anticipation and intellectual disability, is most consistent with which diagnosis?

✓ Correct Answer: Option B

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