A defect in which of the following germ layers would primarily affect the development of the brain, spinal cord, and epidermis?
✓ Correct Answer: Option C
The ectoderm is the outermost germ layer responsible for forming the epidermis, nervous system (brain and spinal cord from the neural tube), and sensory organs. Neural crest cells are derived from the ectoderm but are a specific cell population.
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