A bacterium produces an exotoxin that acts as a superantigen, leading to massive T-cell activation and cytokine release, resulting in symptoms like fever, rash, and hypotension. Which toxin is an example of this mechanism?

Question

BrainForge Quiz · Accepted Answer

C) Toxic shock syndrome toxin-1 (TSST-1). TSST-1, produced by Staphylococcus aureus, is a superantigen that cross-links MHC class II molecules on antigen-presenting cells with T-cell receptor beta chains, causing widespread non-specific T-cell activation and cytokine storm.

A bacterium produces an exotoxin that acts as a superantigen, leading to massive T-cell activation and cytokine release, resulting in symptoms like fever, rash, and hypotension. Which toxin is an example of this mechanism?

✓ Correct Answer: Option C

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