🏥 USMLE Exam Prep

A 75-year-old male undergoes a total hip arthroplasty. He has a history of hypertension and obesity (BMI 35). There are no contraindications to anticoagulation. Which of the following is the most appropriate VTE prophylaxis regimen for this patient?

A Aspirin 81 mg daily
B Intermittent pneumatic compression devices alone
C Low molecular weight heparin (LMWH) or fondaparinux
D Warfarin with an INR target of 2.0-3.0

✓ Correct Answer: Option C

Patients undergoing total hip arthroplasty are at high risk for VTE. Pharmacologic prophylaxis, typically with LMWH or fondaparinux, is recommended in addition to mechanical methods, often for several weeks post-surgery.

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