A 75-year-old male undergoes a total hip arthroplasty. He has a history of hypertension and obesity (BMI 35). There are no contraindications to anticoagulation. Which of the following is the most appropriate VTE prophylaxis regimen for this patient?

The correct answer to the question "A 75-year-old male undergoes a total hip arthroplasty. He has a history of hypertension and obesity (BMI 35). There are no contraindications to anticoagulation. Which of the following is the most appropriate VTE prophylaxis regimen for this patient?" is Option C: Low molecular weight heparin (LMWH) or fondaparinux.

The other options — A) Aspirin 81 mg daily, B) Intermittent pneumatic compression devices alone, D) Warfarin with an INR target of 2.0-3.0 — are incorrect for this USMLE Exam Prep question. As explained above: Patients undergoing total hip arthroplasty are at high risk for VTE. Pharmacologic prophylaxis, typically with LMWH or fondaparinux, is recommended in addition to mechanical methods, often for severa…