A 70-year-old male with a history of COPD is admitted to the hospital with community-acquired pneumonia (CAP). His CURB-65 score is 3. What is the most appropriate empiric antibiotic regimen for this patient?

✓ Correct Answer: Option C

For hospitalized patients with CAP, especially those with comorbidities like COPD or a higher CURB-65 score, empiric treatment typically involves a combination of a beta-lactam (e.g., ceftriaxone) and a macrolide (e.g., azithromycin) or doxycycline, to cover typical and atypical pathogens.