A 70-year-old female presents with confusion and seizures. Her serum sodium is 110 mEq/L. What is the most appropriate initial management to prevent osmotic demyelination syndrome?

✓ Correct Answer: Option B

Severe, symptomatic hyponatremia requires cautious administration of 3% hypertonic saline to slowly raise serum sodium (no more than 4-6 mEq/L in 24 hours) to prevent osmotic demyelination syndrome.