🏥 USMLE Exam Prep

A 70-year-old female on chronic warfarin therapy for atrial fibrillation presents for a routine INR check. Her INR is 4.2. She denies any bleeding, bruising, or other symptoms. Her target INR range is 2.0-3.0. What is the MOST appropriate management?

A Administer 2.5 mg oral vitamin K
B Hold warfarin for 1-2 days and repeat INR
C Administer fresh frozen plasma
D Increase warfarin dose by 25%

✓ Correct Answer: Option B

For an asymptomatic patient with an INR between 4.5 and 10, holding warfarin for 1-2 days and rechecking the INR is the standard recommendation. Vitamin K is generally reserved for INR >10 or bleeding.

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