A 68-year-old woman presents to the emergency department with signs of septic shock, including hypotension (BP 80/50 mmHg), tachycardia (HR 120/min), and altered mental status. After initial fluid resuscitation with 3 liters of normal saline, her blood pressure remains 85/55 mmHg. Her urine output is minimal. Which of the following is the most appropriate next step in management?
✓ Correct Answer: Option B
For patients in septic shock who remain hypotensive despite adequate fluid resuscitation, vasopressors are indicated to maintain mean arterial pressure. Norepinephrine is the first-line vasopressor in septic shock due to its potent alpha-adrenergic effects, increasing vascular tone.