🏥 USMLE Exam Prep

A 68-year-old man with a history of hypertension presents to the emergency department with a 1-day history of generalized weakness, fever of 39.5°C (103.1°F), and confusion. His blood pressure is 85/40 mmHg, heart rate 110 bpm, and respiratory rate 24 bpm. Capillary refill time is prolonged. What is the most immediate critical intervention after securing airway and breathing?

A Administer broad-spectrum antibiotics
B Obtain blood cultures
C Initiate intravenous fluid resuscitation
D Administer norepinephrine via central line

✓ Correct Answer: Option C

For septic shock with hypotension, immediate intravenous fluid resuscitation (e.g., 30 mL/kg crystalloids) is the priority to restore organ perfusion and increase blood pressure. Antibiotics and cultures are also urgent but follow initial fluid bolus.

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