A 68-year-old male with a history of hypertension and Type 2 Diabetes Mellitus has an eGFR of 45 mL/min/1.73m² and a urine albumin-to-creatinine ratio (UACR) of 150 mg/g. His current medications include metformin and atorvastatin. Which medication would be most beneficial to slow the progression of his renal disease?
✓ Correct Answer: Option C
ACE inhibitors (like lisinopril) or ARBs are first-line agents for renoprotection in patients with CKD, particularly those with diabetes and albuminuria, due to their ability to reduce intraglomerular pressure and proteinuria.