🏥 USMLE Exam Prep

A 68-year-old female with a history of heart failure with reduced ejection fraction (HFrEF) presents to the ED with acute worsening dyspnea, orthopnea, and peripheral edema. Her BP is 150/90 mmHg, HR 100 bpm, RR 24 bpm, O2 saturation 92% on room air. Jugular venous distension is noted. Lungs have crackles bilaterally. Which of the following is the MOST appropriate initial pharmacological intervention?

A Intravenous dobutamine
B Intravenous furosemide
C Oral lisinopril
D Oral metoprolol succinate

✓ Correct Answer: Option B

In acute decompensated heart failure with signs of volume overload (dyspnea, orthopnea, edema, JVD, crackles), intravenous loop diuretics like furosemide are the mainstay of initial therapy to reduce preload and alleviate congestion.

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