🏥 USMLE Exam Prep

A 65-year-old male with chronic kidney disease (CKD) presents to the emergency department with generalized weakness and nausea. His EKG shows tall peaked T-waves. Labs reveal K+ 7.2 mEq/L, creatinine 4.5 mg/dL (baseline 2.0 mg/dL). Which of the following is the most appropriate immediate intervention to stabilize the cardiac membrane?

A Intravenous insulin and dextrose
B Intravenous sodium bicarbonate
C Intravenous calcium gluconate
D Oral sodium polystyrene sulfonate

✓ Correct Answer: Option C

Hyperkalemia with EKG changes (peaked T-waves) requires immediate cardiac membrane stabilization. Intravenous calcium gluconate provides rapid stabilization without lowering serum potassium. Insulin/dextrose and sodium bicarbonate shift potassium intracellularly. Sodium polystyrene sulfonate removes potassium from the body but has a delayed effect.

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