🏥 USMLE Exam Prep

A 65-year-old female with a history of diabetes presents to the ED with fever, chills, confusion, and hypotension (BP 85/50 mmHg). Lactate is 4.5 mmol/L. She appears acutely ill. What is the most critical initial intervention?

A Administer broad-spectrum antibiotics
B Obtain cultures (blood, urine)
C Initiate rapid intravenous fluid resuscitation
D Place a central venous catheter for CVP monitoring

✓ Correct Answer: Option C

Rapid intravenous fluid resuscitation (30 mL/kg within the first 3 hours) is the most critical initial intervention in septic shock to improve perfusion, address hypotension, and reduce lactate. Antibiotics and cultures are also vital but often follow or occur concurrently with initial fluid boluses.

Related USMLE Exam Prep Questions