A 62-year-old male presents to the emergency department with acute chest pain and ST-elevation in leads II, III, aVF. He has a history of ischemic stroke 3 months ago. ECG confirms inferior STEMI. The nearest cardiac catheterization lab is 90 minutes away. Which of the following is the most appropriate immediate management regarding reperfusion therapy?

✓ Correct Answer: Option B

Previous ischemic stroke within 3 months is a strong contraindication for fibrinolytic therapy due to increased risk of hemorrhagic conversion. Emergent percutaneous coronary intervention (PCI) is the preferred reperfusion strategy in STEMI, especially when fibrinolysis is contraindicated, and should be pursued as rapidly as possible.