A 60-year-old male with a history of alcoholic cirrhosis presents with massive hematemesis. Initial management includes establishing two large-bore IVs, fluid resuscitation, and ordering packed red blood cells. In addition to these measures, what is the most critical initial pharmacological intervention to manage suspected variceal hemorrhage?
✓ Correct Answer: Option B
Octreotide is critical for variceal bleeding as it causes splanchnic vasoconstriction, reducing portal pressure and variceal blood flow. PPIs are for non-variceal bleeds, and ceftriaxone is for SBP prophylaxis, not initial bleeding control.