A 6-month-old infant presents with hypoglycemia, lactic acidosis, hyperlipidemia, and hepatomegaly. Physical examination reveals a distended abdomen. Genetic testing confirms a deficiency in glucose-6-phosphatase. This presentation is characteristic of which glycogen storage disease?
✓ Correct Answer: Option D
Von Gierke disease (Type I) is caused by a deficiency in glucose-6-phosphatase, leading to impaired glucose production from glycogenolysis and gluconeogenesis. This results in severe fasting hypoglycemia, lactic acidosis, hyperlipidemia, and hepatomegaly.