A 58-year-old man presents with progressive dyspnea on exertion, orthopnea, and paroxysmal nocturnal dyspnea. Physical examination reveals jugular venous distension, crackles at the lung bases, and a laterally displaced point of maximal impulse. His ejection fraction is measured at 30%. Which of the following medications is most likely to improve long-term survival in this patient?

The correct answer to the question "A 58-year-old man presents with progressive dyspnea on exertion, orthopnea, and paroxysmal nocturnal dyspnea. Physical examination reveals jugular venous distension, crackles at the lung bases, and a laterally displaced point of maximal impulse. His ejection fraction is measured at 30%. Which of the following medications is most likely to improve long-term survival in this patient?" is Option C: Lisinopril.

The other options — A) Furosemide, B) Digoxin, D) Hydralazine — are incorrect for this USMLE Exam Prep question. As explained above: Lisinopril, an ACE inhibitor, is a cornerstone of heart failure management, especially with reduced ejection fraction, as it has been shown to improve survival by reducing ventricular remodeling and …